Esomeprazole Magnesium (generic Nexium) proton-pump inhibitor (PPI) drug that suppresses gastric acid secretion by specific inhibition in the gastric parietal cell.
Generic Nexium is a compound that inhibits gastric acid secretion and is indicated in the treatment of gastroesophageal reflux disease (GERD), the healing of erosive esophagitis, and H. pylori eradication to reduce the risk of duodenal ulcer recurrence. Nexium tablets are isomers of omeprazole that is administered in the form of its magnesium salt especially in the treatment of erosive esophagitis, gastroesophageal reflux disease, and duodenal ulcer.
Esomeprazole Magnesium
belongs to a new class of antisecretory compounds, the substituted benzimidazoles, that suppress gastric acid secretion by specific inhibition of the enzyme system at the secretory surface of the gastric parietal cell. Because this enzyme system is regarded as the acid (proton) pump within the gastric mucosa, Esomeprazole has been characterized as a gastric acid-pump inhibitor, in that it blocks the final step of acid production. This effect is dose-related and leads to inhibition of both basal and stimulated acid secretion irrespective of the stimulus.
The recommended adult dose is either 20 or 40 mg esomeprazole given once daily or intravenous infusion (10 to 30 minutes). The admixture should be stored at room temperature up to 30°C (86°F) and should be administered within 6 hours.
Some conditions are treated with a combination of esomeprazole and antibiotics. To best treat your condition, use all of your medications as directed by your doctor. Be sure to read the medication guide or patient instructions provided with each of your medications. Do not change your doses or medication schedule without advice from your doctor.
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Since manufacturers of generic medicines do not incur in the same expenses for product development as the first, they can sell the generic version at a lower price.
Various discount gastrointestinal drugs are commonly used for the many gastrointestinal problems that are routinely seen in men and women. Gastrointestinal meds will hopefully allow the clinician to use them wisely and effectively in the many clinical situations that arise daily in patients with gastrointestinal problems.